On 18 May 1840, Isham Griffin and Robert Hill were bound in the penalty of $200 for Isham Griffin’s administration of the estate of John Griffin, deceased. Signed Isham his x mark Griffin, Ro: Hill. [Essex County, Virginia, Will Book 24, pages 476–477.]

1850 U.S. Census, Essex County, Virginia
Dwelling 640, Family 640
Griffin, Isham, 50, male, farmer, $1,400 real estate, born in Virginia, cannot read or write
Griffin, Sarah, 50, female, born in Virginia, cannot read or write
Griffin, Albert, 22, male, laborer, born in Virginia, cannot read or write
Griffin, Mary, 20, born in Virginia